tankyrase

基本解釋

Tankyrase, a new telomeric poly (ADP ribose) polymerase (PARP), acts as a positive regulator of telomere elongation. It can influence chromosomal stability and is closely related to cell senescence, death and carcinogenesis.
端錨聚合酶 (tankyrase)是一種位于端粒的聚腺苷二磷酸核糖聚合酶 ,它在端粒酶陽(yáng)性細(xì)胞中過(guò)表達(dá)可使端粒長(zhǎng)度增加 ,從而影響染色體的穩(wěn)定性 ,與細(xì)胞的衰老、死亡和癌變密切相關(guān) ;
Expression of Tankyrase mRNA in Three Chemical Carcinogens-induced Malignant Transformed Cells
化學(xué)致癌物轉(zhuǎn)化細(xì)胞端錨聚合酶mRNA的表達(dá)
Tankyrase 1 (TANK1)
端錨蛋白