efflux-pump

常見例句

• Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
  目的:探討主動外排泵在嗜麥芽寡養(yǎng)單胞菌對氟喹諾酮類藥物耐藥中的作用。
• The drug-resistance mechaniam of shigella caused by producing inactived enzyme,changing cell walls,target site structure and active efflux pump.
  志賀菌的耐藥機制主要是產(chǎn)生滅活酶、細胞壁的改變、主動外排以及作用靶位結(jié)構(gòu)的改變。
• ABSTRACT Objective To investigate the role of efflux pump of Acinetobacter baumannii mutant strains against fluoroquinolones.
  目的探討主動外排泵在鮑曼不動桿菌誘導突變株對氟喹諾酮類藥物敏感性的影響。
• P-glycoprotein is an ATP-driven efflux pump which transport a wide variety of structurally diverse compounds from the cell interior into the extracellular space.
  糖蛋白是一個能量依賴性轉(zhuǎn)運蛋白,能將許多結(jié)構(gòu)不同的化合物逆向轉(zhuǎn)運出細胞。
• The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
  AcrAB外流泵系統(tǒng)的合成有多重耐藥調(diào)節(jié)子 (marRAB)調(diào)控 ,AcrAB與多種抗生素的耐藥有關(guān)。 拓撲異構(gòu)酶 (topoisomerase)的突變主要與氟喹諾酮類藥物的耐藥性有關(guān) ,突變主要發(fā)生在gyrA ,parC基因上
• It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
  提示臨床分離的雞大腸桿菌O 78的耐藥水平與喹諾酮類藥物的選擇性壓力有關(guān),它誘導了DNA旋轉(zhuǎn)酶和拓撲異構(gòu)酶IV的基因突變,可能不能激活A crAB外輸泵。
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